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Carboxylic Acid Reactions Practice Problems

Carboxylic acid derivatives practice issues

This is a comprehensive practice problem roofing most of the nucleophilic acyl exchange reactions of carboxylic acids and their derivatives.

Hither is the content of this ane-hour video for the practice problem solutions:

The detailed machinery for reactions such equally Fischer esterification, ester hydrolysis, transesterification, the reaction of carboxylic acids with amines to produce salts and using coupling amanuensis or converting them offset to acyl chlorides using thionyl chlorides to set up amides.

The mechanisms of acrid or base of operations-catalyzed hydrolysis of amides, imines, nitriles, and esters. The similarity and deviation of the Grignard and Organocuprates reactions with esters, acid chlorides, anhydrides and nitriles, and their mechanisms.

Y'all can too find all of these reactions in one powerful summary sheet which is role of the Organic 1 and 2 Summary guides and included in CS memberships.

Reactions of Carboxylic Acids and Carboxylic Acrid Derivatives

This beautiful Summary Guide includes theNucleophilic Acyl Substitution mechanism also referred to every bit anAdd-on-Elimination mechanism,the mechanism ofFischer esterification.

The reaction of esters such as reversible hydrolysisunder acidic and irreversible hydrolysis under basic conditions, transesterification,and all the others with nucleophiles and reducing agents.

You volition accept acomprehensive summary of the grooming and all the major reactions ofCarboxylic Acids, Anhydrides, Esters, Acid (acyl) Chlorides, AmidesandNitriles.All the common patterns, equally well as the details for specific reactions for instance with the Grignard reagent and Organocuprates of each derivative, is addressed in the given section.

Endeavor solving each problem before checking the reply and solution.

Do

1.

Predict the major production for each nucleophilic acyl substitution reaction and draw the corresponding curved-pointer mechanism:

a)

answer

b)

answer

c)

reply

Without a coupling reagent, the carboxylic acid and amine react as acrid and base.

d)

respond

e)

answer

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f)

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g)

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h)

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i)

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j)

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k)

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l)

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k)

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n)

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o)

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p)

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q)

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r)

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south)

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t)

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u)

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v)

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x)

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y)

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z)

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Solution

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2.

Propose reagents for reducing the following carbonyl compounds:

a)

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b)

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c)

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d)

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e)

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f)

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g)

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3.

Predict the major organic product(south) for each of the following reactions. They all involve carboxylic acrid derivatives such equally esters, acrid chlorides, nitriles, anhydrides, and amides. You may also need to go over the reactions covered in earlier capacity, particularly, the Grignard and Gilman reagents, oxidizing and reducing agents and electrophilic aromatic substitutions.

A link to each topic encountered in a given problem will exist provided in the respond tab.

a)

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b)

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c)

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d)

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east)

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;

f)

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1000)

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h)

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i)

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j)

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thousand)

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l)

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Carboxylic Acid Reactions Practice Problems,

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